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What the Public Wants: Pills (March 4, 2008) I have often been critical of the pharmaceutical industry here for a number of excesses pushed in the name of obscene profits: their egregious hyping via "scare" ad campaigns of minor syndromes into horrible diseases you just have to "cure" with their costly new drug; medications which don't work for most people, or which lose their effectiveness in relatively short order; medications which have not been tested in combination with other common drugs patients may be taking, and medications with major under-reported side-effects. Frequent contributor Nurse Dorothy filed this report and made this cogent observation: we're just getting what we want: pills.
When I read your article about over prescription, I wasn't even sure how to describe the chaos in our healthcare system when it comes to meds.Thank you, Dorothy, for your experientially-informed observations. One of the great pleasures of hosting oftwominds.com is receiving informed opinions from those actually working in complex fields. Want to understand today's U.S. Armed Forces? We have correspondents both active duty and retired to share their real-world knowledge. Want to understand the stock market's actions? We are fortunate to have professional traders as correspondents. And so on, in many fields of endeavor--not just in the U.S., but also in the U.K. and other nations as well. So what Dorothy is suggesting is the pharmaceutical industry is responding not just to the goal of profits, but to the cultural demand for a pill solution. And if that pill causes unfortunate side effects, we have another pill for those symptoms, and another pill for the side-effects of that med, and so on down the wormhole. One possible issue I have been pondering is the mindset of "cure." In the 20th century, terrible infectious agents such as polio were in fact "cured" by vaccines and anti-bacteriological medicines--penicillin, et. al. After those stunning successes, it was natural to apply that mindset to other diseases such as cancer and heart disease. But alas, those diseases are mind-bogglingly complex. Infectious agents may be partly responsible for some cancers and heart disease, but the effects are subtle and the result of interactions with extremely complicated systems: the immune system being but one example. In our usual human drive for a reductionist "solution" to complex problems, we have sought a "magic pill" or single medication to "cure" lifestyle and genetically-influenced diseases like diabetes, heart disease and cancer. In some rare instances, a medication or treatment (radiation, etc.) does in fact cure the condition. But more often than not, such hopes are dashed. As Dorothy notes, much of what is prescribed today is not a "cure" in the sense we once hoped for, but some agent to relieve the symptoms of disease. In many other cases, medications are simply helping patients "hold the line": keep the tumor from growing any larger, maintain bone mass, etc. It is these incremental improvements, along with the control of infectious diseases, which have prolonged so many lives. But what of the diseases we influence with our own behavior? As the ancient Chinese saying has it, "All disease comes through the mouth," i.e. what we eat. While this too is a reductionism to be treated warily, there is truth in it in terms of many lifestyle diseases--diseases of wealth and excess, in many cases. Clearly, we need a medical system which encourages people to take responsibility for their own health as opposed to a paternalistic system in which a pill is provided (for a handsome profit) as a "solution" because it is profitable for the industry, essentially demanded by a legal system which places all the burdens on the caregivers and virtually none on the patient, and it's easy for the patient. What kind of system would we have if doctors and nurses were legally able to tell a patient: "There's no pill we can give you to cure your condition. As far as the best medical science can ascertain, the cure is changing your lifestyle. To get well, you need to do X, Y and Z for six months and then we'll monitor your progress. It's really up to you." Not every condition or disease has a lifestyle component, of course; but how many do? What kind of cultural and legal changes will enable the nation to wean itself from the notion that a pill will do the impossible without us having to lift a finger on our own behalf? NOTE: I will be away from my desk until March 3, but will try to post regardless. I will read every email but may be unable to respond; my apologies in advance.
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